Table II.
Univariate predictors of time-to-dpCEPH: Incident dpCEPH cases only
| Predictor | HR | 95% CI | P value |
|---|---|---|---|
| Head circumference Z-score | 0.65 | 0.42-1.00 | .051 |
| Right mid arm circumference | 0.93 | 0.2-1.07 | .32 |
| Right triceps skinfold thickness | 1.05 | 0.97-1.13 | .27 |
| BMI | 0.89 | 0.68-1.17 | .40 |
| BMI Z-score | 0.61 | 0.32-1.14 | .12 |
| Weight Z-score | 0.66 | 0.43-1.03 | .07 |
| Height Z-score | 0.67 | 0.42-1.07 | .09 |
| Albumin (per 1 g/dL increase) | 0.52 | 0.23-1.16 | .11 |
| Total bilirubin (per 1 mg/dL increase) | 1.97 | 1.33-2.90 | .0007 |
| Direct bilirubin (per 1 mg/dL increase) | 0.32 | 0.76-2.28 | .32 |
| AST (per 10 U/L increase) | 1.06 | 1.01-1.10 | .01 |
| ALT (per 10 U/L increase) | 1.00 | 1.00-1.01 | .25 |
| GGTP (per 100 U/L increase) | 1.20 | 1.10-1.31 | <.0001 |
| Platelets (103/mm3) | 0.99 | 0.98-1.00 | .04 |
| INR (per 0.1) | 1.21 | 0.95-1.54 | .12 |
| AST/platelets | 5.93 | 2.30-15.33 | .0002 |
| Neonatal cholestasis | 3.70 | 1.06-12.87 | .04 |
ALT, alanine transaminase; BMI, body mass index; dpCEPH, definite or possible clinically evident portal hypertension; HR, hazard ratio; INR, international normalized ratio; KM, Kaplan-Meier.
Model: Cox proportional hazards model with time-varying covariates (except for neonatal cholestasis, which is fixed).