Figure 2.

Forest plot of unadjusted OR of NEC incidence between early-antibiotics and no-early-antibiotics for each NICU. AB, antibiotics; CI, confidence interval; NEC, necrotizing enterocolitis; NICU, neonatal intensive care unit; OR, odds ratio; Model A, NICU site as the random effect and no adjustment for other fixed-effects; model B, model A with adjustment for gestational age, birth weight, and sex as fixed-effects; model C, model B with additional adjustment for delivery mode, use of antenatal steroids, and Apgar score at 5 min; model D, model C with additional adjustment for initiation time of enteral nutrition and type of enteral nutrition in the first week of life