. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: J Pediatr. 2020 Jun 14;227:128–134.e2. doi: 10.1016/j.jpeds.2020.06.032

Table IV.

NEC incidence in the early antibiotic and no early antibiotic groups by geographic region

	5 Guangdong NICUs		8 non-Guangdong NICUs		6 Western NICUs
Models^*	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
A	0.22 (0.09-0.51)	<.001	0.82 (0.45-1.49)	.49	0.96 (0.52-1.80)	.91
B	0.14 (0.05-0.35)	<000	0.34 (0.17-0.69)	<.01	0.39 (0.19-0.81)	<.05
C	0.13 (0.05-0.34)	<.000	0.32 (0.15-0.70)	<.01	0.38 (0.17-0.87)	<.05
D	0.11 (0.04-0.32)	<.000	0.33 (0.15-0.72)	<.01	0.39 (0.17-0.89)	<.05

Adjustment of models: model A. NICU as the random effect and no adjustment for other fixed effects, model B, model A with adjustments for gestational age, birth weight, and sex as fixed effects, model C. model B with additional adjustments for delivery model, use of antenatal steroids, and Apgar score at 5 min; model D, model C with additional adjustments for time of initiation of enteral nutrition and type of enteral nutrition in the first week of life.