Table 2.

Schedule of Assessments

Primary Screening	Secondary Screening	Baseline	Week 8	Week 16	Week 24c	Week 48
Assessment of basic eligibility criteria Symptom quantification	Cognitive testing Functional testing Neurological exam Geriatric syndromes assessment Clinical labs	Primary outcome measures Mediators & moderators Clinical labsa MRIb	Primary outcome measures Mediators & moderators Clinical labsa MRIb	Primary outcome measures Mediators & moderators Clinical labsa MRIb	Primary outcome measures Mediators & moderators	Primary outcome measures Mediators & moderators Neurological exam Clinical labsa

^aPlasma HIV RNA and lymphocyte subset panel only

^bn=30 participants per arm

^cControl participants only