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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Immunol. 2020 Oct 30;205(11):3107–3121. doi: 10.4049/jimmunol.2000882

Fig 2. Changes to the immune response in the uterus and spleen during pregnancy and ZIKV infection.

Fig 2.

Flow cytometry was performed on immune cells from the uteruses and spleens of ZIKV-infected (red triangles) and mock-infected (blue circles) pregnant and non-pregnant mice at day 3 post infection, and the frequencies of CD68+ (a-b), CD11b+ (c), and CD11c+ (d) cells were measured. Representative pseudocolor plots of CD68 gating are shown for the (a) (uterus) and (b) (spleen). *p<0.05, **p <0.01, ***p<0.001; one-way ANOVA and Tukey’s multiple comparisons test. N=39 (2 independent experiments of 19–20 mice, N=8 mock non-pregnant, N=11 mock pregnant, N=10 ZIKV non-pregnant, N=10 ZIKV pregnant). Error bars represent the mean ± standard deviation.