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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Immunol. 2020 Oct 30;205(11):3107–3121. doi: 10.4049/jimmunol.2000882

Fig 3. Pregnant mice have higher frequencies of CD11b+ CD11c+ dendritic cells in the uterus.

Fig 3.

Flow cytometry was performed on the uterine (a-b, e-f) and splenic (c-d, g-h) immune cells of ZIKV-infected (red triangles) and mock-infected (blue circles) pregnant and non-pregnant mice at day 3 post infection. Frequencies of CD11b+ CD11c+ cells (a,c), CD11b+ CD11c+ MHCII+ cells (b,d) CD86+ CD11b+ CD11c+ MHCII+ cells (e,g), and IL-10+ CD11b+ CD11c+ MHCII+ (f,h) cells were measured. Representative flow cytometry plots are also shown in (a) (CD11b+ CD11c+ gating) and (e) (CD86+ gating). *p<0.05, **p<0.01, ***p<0.001; one-way ANOVA and Tukey’s multiple comparisons test. N=40 (2 independent experiments of 20 mice, N=7 mock non-pregnant, N=13 mock pregnant, N=7 ZIKV non-pregnant, N=13 ZIKV pregnant). Error bars represent the mean ± standard deviation.