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. 2020 Nov 24;10:20428. doi: 10.1038/s41598-020-76971-w

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© The Author(s) 2020, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Weight change of the electrospun fiber under PBS (pH 7.4) (a), UV spectra change and representative color change of the PBS solution after immersing the core–shell fibrous sheet (b,c), and methylene blue release profile from the electrospun scaffolds (d). The photo was taken by first author Tuerdimaimaiti Abudula. Overall results imply the role of PCL shell layer coating on the CL based hybrid scaffold in preventing burst release and providing prolonged drug release profile.