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. 2020 Nov 24;10:20486. doi: 10.1038/s41598-020-77191-y

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cell viability (MTT assay) of TT1 cells (a) and ICs (b–d) exposed to 50 nm PS-NH₂ and PS-COOH particles for 24 h. Data are given as percentage with respect to controls (means ± SD). Stars indicate significant differences (p < 0.05) in treated cells with respect to controls according to the Kruskal–Wallis followed by the Dunn’s post hoc test. n = 6 replicates per treatment. LC50 values were calculated through Probit analysis.