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. 2020 Nov 24;10:20436. doi: 10.1038/s41598-020-77374-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Specific primary bile acid differences in serum and faeces. The percentage of total serum bile acids is shown, in (A) unconjugated chenodeoxycholic acid (CDCA); (B) unconjugated cholic acid (CA). Concentration in faeces is shown in (C) CDCA; (D) CA. Each figure shows medians, 25th and 75th centiles, and ranges for IBS-D and BAD patients. P-values are for comparisons of the two groups by Mann–Whitney testing.