Table 4.
Faecal bile acids in patients with IBS-D or bile acid diarrhoea.
| BA concentration (nmol∙g−1) | IBS-D | BAD | P values | ||
|---|---|---|---|---|---|
| Median | IQR | Median | IQR | ||
| Total faecal BA | 4716 | (2259–6168) | 9170 | (7791–14,118) | 0.01 |
| Primary BA | 246 | (107–476) | 1502 | (299–7222) | 0.03 |
| CA | 86 | (61–266) | 995 | (129–3544) | 0.05 |
| CDCA | 149 | (48–256) | 523 | (184–1961) | 0.04 |
| Secondary BA | 4412 | (1979–5725) | 7130 | (3200–9626) | 0.14 |
| DCA | 3661 | (1234–4670) | 5295 | (2734–7469) | 0.14 |
| LCA | 766 | (675–1240) | 1447 | (466–2338) | 0.25 |
| UDCA | 17 | (9–52) | 232 | (27–702) | 0.06 |
| Glycoconjugates | 67 | (29–168) | 79 | (61–107) | 0.81 |
| Tauroconjugates | 26 | (17–59) | 25 | (12–95) | 0.93 |
| Sulfoconjugates | 30 | (13–91) | 101 | (73–553) | 0.03 |
| Unconjugated BA–Urso | 4484 | (2132–5793) | 8465 | (7145–11,723) | 0.01 |
| Ratio primary/secondary | 0.08 | (0.03–0.13) | 0.19 | (0.04–5.26) | 0.37 |
BA were measured in a single stool sample from patients with IBS-D with (SeHCAT > 15%; n = 9), or BAD (SeHCAT < 15%; n = 10).
Comparisons were made by Mann–Whitney U-tests.
P values < 0.05 are shown in bold.