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. 2020 Nov 24;11:5957. doi: 10.1038/s41467-020-19725-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a SEM images of 3D mechanically interlocked structures comprised of fully metallic Fe and PDMS components, highlighting the high-resolution features and possibility of designing completely independent shapes. The scale bar is 50 μm. b Optical images of structures comprised of different polymeric materials. The possibility of using different materials such as shape-memory polymers (SMPs), PDMS, and pure gelatin, possibly loaded with drugs, enables the fabrication of structures suitable for advanced functionalities, such as drug delivery and pre-programmable shape transformation. The use of an interlocking strategy guarantees process compatibility between metal and polymer deposition. As a result, the enhanced magnetic responsiveness and biocompatibility characteristic of fully metallic Fe structures can be harnessed in parallel. The scale bar is 80 μm. c In addition, hybrid microstructures can be mechanically stitched along the X-Y plane to prepare large meshes or filaments. This strategy is suitable to control the agglomeration of magnetic microparticles. The scale bar is 500 μm.