Table 2.

Correlation of the virus reservoir with CyTOF markers´ expression on CD8 + and CD4 + T cells isolated from patients starting ART at the acute and chronic phase of infection.

Marker	CD8 + T cells						CD4 + T cells
	EA		LA		All patients		EA		LA		All patients
	rho	p	rho	p	rho	p	rho	p	rho	p	rho	p
CCR4	− 0.685	0.035	− 0.224	0.537	− 0.552	0.013	− 0.261	0.470	− 0.273	0.448	− 0.359	0.120
CCR5	0.018	0.973	− 0.467	0.178	− 0.474	0.036	− 0.055	0.892	− 0.333	0.349	− 0.430	0.060
CCR6	0.067	0.865	0.285	0.427	− 0.367	0.112	− 0.236	0.514	0.321	0.368	− 0.123	0.603
CD127	− 0.321	0.368	− 0.564	0.096	− 0.504	0.025	0.042	0.919	0.018	0.973	− 0.165	0.484
CD161	− 0.285	0.427	0.527	0.123	− 0.132	0.577	− 0.467	0.178	0.309	0.387	− 0.101	0.672
CD27	− 0.418	0.232	− 0.673	0.039	− 0.507	0.024	− 0.636	0.054	− 0.248	0.492	− 0.340	0.143
CD28	− 0.418	0.232	− 0.648	0.049	− 0.484	0.032	− 0.515	0.133	− 0.139	0.707	− 0.377	0.102
CD31	− 0.055	0.892	− 0.152	0.682	− 0.242	0.302	− 0.103	0.785	0.127	0.733	− 0.095	0.691
CD38	0.103	0.785	0.079	0.838	0.011	0.967	− 0.248	0.492	− 0.006	1.000	0.146	0.538
CD39	0.479	0.166	0.564	0.096	0.128	0.590	0.539	0.113	0.273	0.448	− 0.003	0.992
CD4	− 0.624	0.060	0.091	0.811	− 0.544	0.014	NA	NA	NA	NA	NA	NA
CD3	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
CD44	0.333	0.349	0.794	0.010	0.245	0.296	0.176	0.632	− 0.345	0.331	0.152	0.521
CD45	0.576	0.088	0.127	0.733	0.568	0.010	− 0.224	0.537	0.248	0.492	0.504	0.025
CD45RA	− 0.406	0.247	0.539	0.113	0.030	0.901	0.515	0.133	− 0.152	0.682	− 0.140	0.555
CD5	0.564	0.096	− 0.321	0.368	0.164	0.488	0.370	0.296	0.321	0.368	0.155	0.513
CD57	0.382	0.279	0.576	0.088	0.436	0.056	− 0.406	0.247	0.030	0.946	0.420	0.067
CD8	NA	NA	NA	NA	NA	NA	− 0.176	0.632	0.067	0.865	− 0.105	0.658
CTLA-4	− 0.745	0.018	− 0.297	0.407	− 0.644	0.003	− 0.600	0.073	− 0.091	0.811	− 0.368	0.111
CXCR3	0.406	0.247	0.455	0.191	0.275	0.239	0.503	0.143	0.333	0.349	0.395	0.085
CXCR5	− 0.176	0.632	− 0.067	0.865	− 0.469	0.038	− 0.527	0.123	− 0.067	0.865	− 0.454	0.046
HLA-DR	0.358	0.313	− 0.188	0.608	0.005	0.987	0.152	0.682	− 0.624	0.060	− 0.020	0.937
ICOS	− 0.248	0.492	0.103	0.785	− 0.233	0.321	0.018	0.973	− 0.152	0.682	− 0.095	0.691
Ki-67	− 0.006	1.000	0.152	0.682	0.250	0.287	− 0.539	0.113	0.164	0.657	− 0.268	0.253
PD-1	− 0.152	0.682	0.091	0.811	0.002	0.997	0.212	0.560	0.103	0.785	− 0.084	0.724
TCRab	− 0.442	0.204	0.236	0.514	− 0.101	0.672	− 0.030	0.946	− 0.042	0.919	− 0.030	0.901

Non T cell-specific markers, CD19 and CD11c, were excluded.

EA early ART at acute infection, LA late ART at chronic infection, NA not applicable.