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. 2020 Nov 11;7:583587. doi: 10.3389/fmolb.2020.583587

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Copyright © 2020 Chong, Tan and Tan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytotoxicity of NS-CTX, NK-CTX, and 5-fluorouracil (5FU) on cancer and normal cell lines. (A) Cell viability plot for cancer cell lines (A549, PC-3, and MCF-7). (B) Cell viability plot for normal cell lines (NL20, RWPE-1, and 184B5). (C) Half maximal inhibitory concentrations (IC₅₀) of cell lines treated with NS-CTX and NK-CTX. All assays involved three technical and biological triplicates. One-way ANOVA with Bonferroni post hoc test was used to determine statistical significance across three cancer cell lines (*** indicates p < 0.001).