Table 2.
Multivariate survival analyses of patients with colorectal cancer in the training and validation cohorts.
| Variables | Training cohort | Validation cohort | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | *P value | HR | 95% CI | P value* | |
| Sex | 1.147 | 1.147 (1.045–1.259) | 0.004 | 1.154 | 1.154 (1.005–1.325) | 0.042 |
| Age, year | 1.508 | 1.508 (1.372–1.658) | <0.001 | 1.765 | 1.765 (1.532–2.035) | <0.001 |
| Size, cm | 1.068 | 1.068 (0.983–1.160) | 0.120 | – | – | – |
| Histological grade | 1.181 | 1.181 (1.110–1.258) | <0.001 | 1.094 | 1.094 (0.992–1.205) | 0.071 |
| pT stage | 1.574 | 1.574 (1.487–1.665) | <0.001 | 1.58 | 1.58 (1.453–1.718) | <0.001 |
| TD status | 1.170 | 1.170 (1.035–1.323) | 0.012 | 1.375 | 1.375 (1.147–1.649) | 0.001 |
| Retrieved LNs | 0.568 | 0.568 (0.498–0.647) | <0.001 | 0.675 | 0.675 (0.554–0.821) | <0.001 |
| pN stage | 1.249 | 1.249 (1.209–1.290) | <0.001 | 1.174 | 1.174 (1.120–1.231) | <0.001 |
CI, confidence interval; HR, hazard ratios; LNs: lymph nodes, mpN, modified pathological N; OS, overall survival; pN, pathological N.
*P value based on multivariate Cox proportional hazard models.