Table 5.
Comparison with Similar Studies in South Asia.
| Author (Year) | Present study(2017) | Banerjee (2018) | Ramachandran (2016) | Pai Jakribettu (2015) | Kumar (2010) | Kamath (2006) | Ratageri (2005) | Shah (2004) | Narayanan (2002) | Sajid (2012) | Ahmed (2008) | Alam (2010) | Pervin (2004) | Ahmed (2001) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Country | Sri Lanka | India | India | India | India | India | India | India | India | Pakistan | Pakistan | Bangladesh | Bangladesh | Bangladesh |
| Study design | Retrospective | Prospective | Retrospective | Retrospective | Retrospective | Retrospective | Retrospective | Prospective | Prospective | Prospective | Prospective | Prospective | Prospective | Prospective |
| Sample size | 305 | 200 | 69 | 69 | 359 adults (≥15) and 107 pediatric (<15) cases | 109 DHF III-IV/DSS cases | 23 | 39 | 59 | 35 | 35 | 54 | 97 | 72 |
| Male% | 60.30% | 58.00% | 62.3% | 69.57% | 64.6% | 50.46% | 48% | N/A | 52.54% | 57.14% | 54.29% | 50.00% | N/A | 58.33% |
| Female% | 39.70% | 42.00% | 37.7% | 30.43% | 35.4% | 49.54% | 52% | N/A | 47.46% | 42.86% | 45.71% | 50.00% | N/A | 41.67% |
| Mean duration of fever (days) | 3.9 | N/A | N/A | N/A | 6-10 days | N/A | N/A | 7.7 | 4.9 | N/A | N/A | 4.9 | N/A | 8.2 |
| DF | 80.70% | N/A | N/A | N/A | 83.9% | N/A | 17% | 2.6% | 72.88% | N/A | 31.43% | 40% | N/A | 36.11% |
| DHF | 19.30% | N/A | N/A | N/A | 8.8% | 100.00% | 83% | 97.4% | 27.12% | N/A | 68.57% | 59.3% | 18.56% | 63.89% |
| Cardiac | None | N/A | N/A | N/A | N/A | 4.59% | N/A | N/A | Bradycardia = 10.17% | N/A | N/A | N/A | N/A | N/A |
| Neurological | None | N/A | N/A | N/A | Altered sensorium = 10.3% | 22.02% | 22% | 48.7% | 23.73% | N/A | 2.86% | N/A | N/A | N/A |
| Renal | None | N/A | 39.1% | N/A | Renal failure = 0.2% | 4.59% | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Hepatic | Mild = 62.6%, Moderate = 3% | N/A | 50.7% | 4.35% | 53.2% | 36.70% | 87% | 97.4% | 52.54% | 54.29% | 37.14% | 31.48% | 13.40% | 50.00% |
| Headache | 55.10% | 55.50% | N/A | 52.17% | 47.6% | N/A | 22% | N/A | 28.81% | N/A | 40.00% | 31.48% | 82.47% | 77.78% |
| Bodyache | 52.50% | 63.00% | N/A | 100.00% | 64.6% | N/A | N/A | N/A | 54.24% | 5.71% | 34.29% | 46.30% | 84.54% | 76.39% |
| Nausea | 21.30% | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Vomiting | 43.10% | N/A | 63.8% | 42.03% | 47.6% | N/A | 82% | 86.6% | 83.05% | 34.29% | 68.57% | N/A | 36.08% | 12.50% |
| Diarrhea | 15.40% | N/A | N/A | 8.69% | 13.9% | N/A | 13% | 48.7% | N/A | 17.14% | N/A | 9.26% | N/A | 19.44% |
| Abdominal pain | 21.60% | N/A | 71.0% | 11.59% | 37.5% | N/A | 61% | N/A | 23.73% | 51.43% | 68.57% | 59.26% | 6.19% | N/A |
| Bleeding manifestations | 2.60% | 13.00% | Mucosal bleeding = 39.1% | N/A | Petechiae 67.2%, ecchymosis 6.2%, gum bleeding 5.2%, hematuria 4.9%, melena 4.7%, hematemesis 3%, and epistaxis 2.6% | N/A | N/A | 53.8% | 66.10% | 5.71% | 62.86% | 59.26% | N/A | 86.11% |
| Right hypochondrial tenderness | 38.00% | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Epigastric tenderness | 6.90% | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Platelet count | Count < 25 × 109/L = 10.5%; Count < 100 × 109/L = 58.4% | N/A | Count<100 × 109/L = 82.6% | N/A | N/A | N/A | Count<100 × 10^9/L=82% | “Thrombocytopenia” = 92.3% | Count < 100 × 109/L = 72.88%; Count < 50 × 109/L = 20.34% | Count < 50 × 109/L = 11.43% | Count < 150 × 109/L = 85.71% | Count < 50 × 109/L = 68.52%; Count < 20 × 109/L = 9.26% | Count < 100 × 109/L = 22.68% | Count < 100 × 109/L = 37.5% |
| WBC count | Count < 4 × 106/L = 71.5% | N/A | N/A | N/A | N/A | N/A | Count<5 × 106/L=26% | N/A | Lymphocyte count > 50% = 30.51% | Count < 4 × 106/L = 14.29% | Count < 4 × 106/L = 42.86%; Neutrophils > 60% = 20.00% | Count < 4 × 106/L = 9.26% | N/A | Leucopenia = 12.5% |
| Mortality | None | N = 3 | N = 4 | N = 2 | N = 11 | N = 9 | N = 0 | N = 3 | N = 2 | N = 0 | N = 1 | 6% | N/A | N = 5 |
Note. N/A: not available.