Table 2.

Univariate and multivariable predictors of hospitalization for heart failure.

	Univariate		Multivariate
			Model 1		Model 2
Parameters	HR	p	HR	p	HR	p
Age	1.001 (0.97–1.03)	0.92
Gender	0.49 (0.22–1.15)	0.1
SBP	0.96 (0.92–0.99)	0.04	0.96 (0.92–1.01)	0.128	0.97 (0.93–1.02)	0.26
Right atria area	1.02 (0.96–1.08)	0.05
Digoxin use.	2.71 (1.11–6.58)	0.02	1.46 (0.47–4.53)	0.512	1.25 (0.37–4.16)	0.71
REVEAL risk score	4.62 (2.21–9.68)	0.0001	4.39 (1.57–12.2)	0.005	1.41 (1.13–1.77)	0.003
GDF-15	4.02 (2.01–10.03)	0.0001	3.48 (1.01–11.98)	0.04
GDF-15 > 1000 ng/l	5.84 (2.23–15.28)	0.0001			5.46 (1.69–17.6)	0.004

Notes: Model 1: GDF-15 as a continuous variant; Model 2: GDF-15 > 1000 ng/l as a binary variant. Adjusted by age and gender.

SBP: systolic blood pressure; GDF-15: growth differentiation factor-15.