Fig. 3.

Inhibited NEAT1 or elevated miR-129-5p suppresses blood lipid and inflammation reaction in ASH mice. A, expression of NEAT1, miR-129-5p, and SOCS2 in mice’s liver tissues of each group; B, contents of ALT and AST in mice’s serum in each group; C, contents of TG and TC in mice’s serum in each group; D, contents of TNF-α, IL-1β, and IL-6 in mice’s serum in each group; *P < 0.05 vs the control group, ^#P < 0.05 vs the siRNA-NC group, ^&P < 0.05 vs the agomiR-NC group, ^$P < 0.05 vs the oe-NEAT1 + agomiR-NC group; n = 10, the measurement data were expressed as mean ± standard deviation, one-way ANOVA was used for comparisons among multiple groups, and Tukey’s post hoc test was used for pairwise comparisons after one-way ANOVA