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. 2020 Nov 11;11:526349. doi: 10.3389/fphar.2020.526349

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Copyright © 2020 Ke, Zhan, Lu, Zhou, Chen, Dong, Lv and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LDOP-1 inhibited the expression of Bax, caspase 3 and boost of Bcl-2. (A) The expression of Bax and Bcl₂ detected by Western blot. (B) Statistical analysis on ratio of Bax to Bcl-2. (C) The production of caspase 3 detected by biochemical markers kit. (D) Immunohistochemical image of Bcl₂ measured by immunofluorescence technique. Data are expressed as the mean ± SD of three independent experiments. ^##P < 0.01, ^###P<0.001 compare the control group; **P < 0.01 compare model group. ^$P < 0.05 compare with LDOP-1 group. LDOP stood for LDOP-1.