Table 1.

Resistance to Coccidioides infection in specific strains could be due to immune cellularity differences.

Mouse Background	Susceptibility to Coccidioides Infection	Alveolar Macrophage Freq.	Lung-resident DC Freq.	Respiratory Leukocyte TNFα production	Respiratory Leukocyte IL-10 production	Lung CD4+CD25+FOXP3+ (Treg) Freq.	Reference Numbers
C57BL/6	Susceptible	Base	Base	Base	Base	Base	(Fierer et al., 1998; Viriyakosol et al., 2008; Viriyakosol et al., 2013; Hung et al., 2014b)
BALB/C	Susceptible	No Δ	No Δ	↑↑	↑↑	↑↑	(Fierer et al., 1998; Viriyakosol et al., 2008; Hung et al., 2014b)
DBA/2	Resistant	No Δ	No Δ	No Δ	↓	↓	(Fierer et al., 1998; Viriyakosol et al., 2008; Viriyakosol et al., 2013; Hung et al., 2014b)

The base frequency of cells or cytokine production is in reference to C57BL/6 mice; denoted changes are relative to this strain. Cytokine production was measured post stimulation ex vivo. No Δ, no change from base level; ↑↑, higher than base; ↓, less than base.