Table 3.

Cox regression analyses for factors predicting the progression of COVID-19

Covariate	HR (95% CI)	P
Age, years	1.038 (1.002–1.075)	0.039
Hypertension	2.295 (0.765–6.881)	0.138
Fever	1.278 (0.161–10.146)	0.816
Cough	3.336 (0.734–15.160)	0.119
C-reactive protein, mg/L	1.018 (1.005–1.030)	0.004
Procalcitonin, ng/ml	1.356 (1.092–1.684)	0.006
T lymphocyte count, /μl	0.999 (0.997–1.000)	0.119
CD4+ lymphocyte count, /μl	0.998 (0.995–1.001)	0.148
CD8+ lymphocyte count, /μl	0.998 (0.994–1.001)	0.192
B lymphocyte count, /μl	0.993 (0.984–1.002)	0.133
NK lymphocyte count, /μl	0.996 (0.989–1.002)	0.205
IL-6, pg/ml	1.021 (1.004–1.039)	0.014
Lactate, mmol/L	1.023 (1.004–1.043)	0.018
NLR	0.995 (0.904–1.095)	0.921
CD4+/total T lymphocyte	1.089 (0.041–29.038)	0.959
CD8+/total T lymphocyte	1.121 (0.019–67.083)	0.956

Bold indicates the difference is statistically significant

COVID-19 coronavirus disease 2019, IL-6 interleukin-6, NLR neutrophils/lymphocytes ratio, HR hazard ratio, CI confidence interval