Figure 2.

(a) Hemoglobin (Hb) concentrations (g/dL) in individuals with different haplotypes estimated from four EGLN1 SNPs (rs2486740, rs508618, rs12097901, and rs1769792) in the entire cohort. White dots represent mean Hb concentration values and bold black bars represent median values. The Hb measurement data were obtained by using a noninvasive method. (b) Relationship between the estimated Hb concentration and EGLN1 haplotype frequency in all subjects (upper graph) and male or female subjects (bottom graphs) in the entire cohort. Hb levels are represented as the mean ± standarddeviation of the mean. The bold blue line represents the regression line.