Table 4.
Haplotype frequencies estimated from four SNPs around EGLN1 and hemoglobin levels in Bolivian highlanders.
| Haplotypea | 2Nb | Frequency | Hb level (g/dL)c |
|---|---|---|---|
| TGCG | 83d | 0.424 | 14.60 ± 1.37d |
| CACA | 28d | 0.146 | 14.25 ± 1.28d |
| TACG | 19 | 0.096 | 14.53 ± 1.28 |
| TGGA | 18 | 0.091 | 14.73 ± 1.54 |
| TGCA | 15 | 0.076 | 14.21 ± 1.41 |
| CACG | 13 | 0.066 | 14.15 ± 1.61 |
| CAGA | 10 | 0.051 | 13.70 ± 1.07 |
| TACA | 3 | 0.015 | 13.17 ± 1.42 |
| TGGG | 2 | 0.010 | 13.70 ± 1.70 |
| TAGA | 2 | 0.010 | 13.40 ± 0.14 |
| TAGG | 2 | 0.010 | 12.65 ± 1.34 |
| CGCA | 1 | 0.005 | 11.70 ± 0.00 |
Abbreviations: SNP—single-nucleotide polymorphism. Hb—hemoglobin. aHaplotype consists of four SNPs examined (from left, rs2486740, rs508618, rs12097901, and rs1769792). bThe number of chromosomes. cEstimated values obtained by using a noninvasive method (the mean ± standarddeviation of the mean). dOne individual was removed due to a lack of Hb measurement.