Table 5.

Haplotype frequencies estimated from four SNPs around EGLN1 and Hb levels in 48 male and 50 female Bolivian highlanders.

Sex	Haplotypea	2Nb	Frequency	Hb level (g/dL)c
Men	TGCG	46d	0.479	15.53 ± 0.77d
	TGGA	13	0.135	15.41 ± 0.83
	CACA	12d	0.125	15.76 ± 0.51d
	TACG	8	0.083	15.44 ± 0.89
	TGCA	7	0.073	15.17 ± 0.84
	CACG	7	0.073	15.29 ± 0.83
	CAGA	3	0.031	14.90 ± 0.26
Women	TGCG	37	0.370	13.46 ± 1.04
	CACA	16	0.160	13.38 ± 0.75
	TACG	11	0.110	13.63 ± 0.80
	TGCA	8	0.080	12.88 ± 1.34
	CAGA	7	0.070	13.36 ± 1.27
	CACG	6	0.060	12.82 ± 1.22
	TGGA	5	0.050	13.19 ± 0.82
	TACA	3	0.030	13.17 ± 1.42
	TGGG	2	0.020	13.70 ± 1.70
	TAGA	2	0.020	13.40 ± 0.14
	TAGG	2	0.020	12.65 ± 1.34
	CGCA	1	0.010	11.70 ± 0.00

Abbreviations: SNP—single-nucleotide polymorphism. Hb—hemoglobin. ^aHaplotype consists of four SNPs examined (from left, rs2486740, rs508618, rs12097901, and rs1769792). ^bThe number of chromosomes. ^cEstimated values obtained by using a noninvasive method (the mean ± standarddeviation of the mean). ^dOne individual was removed due to a lack of Hb measurement.