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. 2020 Nov 25;2020:7079356. doi: 10.1155/2020/7079356

Table 2.

List of CTL epitopes that have good combined score and are antigenic, nonallergic, and immunogenic, and bind with an affinity IC50 value of less than 200 with the MHC-I alleles.

Epitopes Position in sequence Combined score Interaction of MHC-I allele with an affinity IC50 value of <200 Immunogenicity Antigenic Allergen Toxic Population coverage (%) Binding score (kcal/mol) of epitopes with MHC-I
FLAFVVFLL 20 1.44 HLA-A02:01
HLA-A02:06
HLA-B15:02
HLA-C03:03
HLA-A68:02
0.30 Yes No No 48.4 −61.8

FLLVTLAIL 26 1.42 HLA-C03:03
HLA-A02:01
HLA-B15:02
HLA-C14:02
HLA-A02:06
0.17 Yes No No 48.4 −57.2

LLFLAFVVF 18 1.25 HLA-B15:01
HLA-A32:01
HLA-C12:03
HLA-C14:02
HLA-B15:02
HLA-C03:03
0.23 Yes No No 32.5 −43.31

VLLFLAFVV 17 1.12 HLA-A02:01
HLA-A02:06
HLA-C12:03
HLA-C14:02
0.26 Yes No No 48.4 −80.3

SVLLFLAFV 16 1.05 HLA-A02:06
HLA-C12:03
HLA-A02:01
HLA-A68:02
0.19 Yes No No 32.5 −60.31