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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Clin Cancer Res. 2020 Jul 28;26(20):5424–5437. doi: 10.1158/1078-0432.CCR-20-0851

Figure 1. Synthesis and characterization of DFO-Gef-C’ dots.

Figure 1.

a) Molecular rendering of Gef-C’ dots. b) Chemical structure of azido-dPEG8-Phe-Lys-PABC-APdMG Drug-Linker. c) Representative TEM image of DFO-Gef-C’ dots. d) A representative UV-Vis absorbance spectrum of DFO-Gef-C’ dots (DPR 40). e) FCS correlation curve with fit of DFO-Gef-C’ dots (DPR 40). f) Payload stability monitoring of DFO-Gef-C’ dots in PBS over one month at 4 °C. g) Payload stability of DFO-Gef-C’ dots in mouse and human serum at 37 °C under shaking (650 rpm).