Figure 2. Renal/hepatic clearance and biodistribution of 89Zr-DFO-Gef-C’ dots (DPR 40) in healthy mice after i.v. administration.

a) Biodistribution of 89Zr-DFO-Gef-C’ dots in major organs and tissues on day 7, expressed in terms of %ID (n=3; error bars: mean±SD). Inset shows the cumulative clearance measurements of 89Zr-DFO-Gef-C’ dots in urine and feces at various p.i. time points (n=3; error bars: mean±SD). b) Biodistribution of 89Zr-DFO-Gef-C’ dots in healthy mice (n=3) at 4, 24 and 72 h post-injection.