Table 1.
Characteristic | Before matching | After matching | ||||||
---|---|---|---|---|---|---|---|---|
All patients (n = 1,113) | Patients with GI symptoms (n = 369) | Patients without GI symptoms (n = 744) | p-value | All patients (n = 1,077) | Patients with GI symptoms (n = 359) | Patients without GI symptoms (n = 718) | p-value | |
Age, year | ||||||||
Median (IQR) | 59.0 (47.0–68.0) |
61.0 (50.0–70.0) |
57.5 (46.0–67.0) |
<0.001 | 59.0 (47.0–68.0) |
60.0 (48.0–70.0) |
59.0 (47.0–67.0) |
0.065 |
Distribution, n (%) | ||||||||
<15 | 0 | 0 | 0 | 0 | 0 | 0 | ||
15–44 | 238 (21.4) | 65 (17.6) | 173 (23.3) | 219 (20.0) | 65 (18.1) | 154 (21.5) | ||
45–64 | 476 (42.8) | 152 (41.2) | 324 (43.5) | 476 (42.7) | 152 (42.3) | 324 (45.1) | ||
≥65 | 399 (35.8) | 152 (41.2) | 247 (33.2) | 382 (34.3) | 142 (39.6) | 240 (33.4) | ||
Sex, n (%) | 0.496 | 0.763 | ||||||
Male | 550 (49.4) | 177 (48.0) | 373 (50.1) | 532 (49.4) | 175 (48.7) | 357 (49.7) | ||
Female | 563 (50.6) | 192 (52.0) | 371 (49.9) | 545 (50.6) | 184 (51.3) | 361 (50.3) | ||
Exposure history, n (%) | 153 (13.7) | 49 (13.3) | 104 (14.0) | 0.750 | 152 (14.1) | 48 (13.4) | 104 (14.5) | 0.621 |
Comorbidity, n (%) | 574 (51.6) | 203 (55.0) | 371 (49.9) | 0.106 | 557 (51.7) | 193 (53.8) | 364 (50.7) | 0.343 |
Hypertension | 368 (33.1) | 133 (36.0) | 235 (31.6) | 0.137 | 355 (33.0) | 124 (34.5) | 231 (32.2) | 0.436 |
Diabetes | 150 (13.5) | 59 (16.0) | 91 (12.2) | 0.084 | 145 (13.5) | 55 (15.3) | 90 (12.5) | 0.207 |
CHD | 91 (8.2) | 32 (8.7) | 59 (7.9) | 0.671 | 86 (8.0) | 29 (8.1) | 57 (7.9) | 0.937 |
Cerebrovascular disease | 31 (2.8) | 12 (3.3) | 19 (2.6) | 0.505 | 27 (2.5) | 10 (2.8) | 17 (2.4) | 0.683 |
Chronic heart failure | 35 (3.1) | 18 (4.9) | 17 (2.3) | 0.020 | 32 (3.0) | 16 (4.5) | 16 (2.2) | 0.042 |
Liver dysfunction | 89 (8.0) | 29 (7.9) | 60 (8.1) | 0.905 | 87 (8.1) | 28 (7.8) | 59 (8.2) | 0.812 |
CKD | 57 (5.1) | 29 (7.9) | 28 (3.8) | 0.004 | 52 (4.8) | 25 (7.0) | 27 (3.8) | 0.056 |
Chronic pulmonary disease | 59 (5.3) | 27 (7.3) | 32 (4.3) | 0.035 | 58 (5.4) | 26 (7.2) | 32 (4.5) | 0.174 |
Data are shown as median (IQR) or n (%). p-values were calculated using Mann-Whitney U-test, χ2-test, or Fisher's exact-test, as appropriate. GI, gastrointestinal; CHD, Coronary heart disease; CKD, Chronic kidney disease.