Table 3.
Laboratory and radiographic findings of patients with COVID-19 with and without GI symptoms.
| All patients (n = 1,077) | Patients with GI symptoms (n = 359) | Patients without GI symptoms (n = 718) | p-value | |
|---|---|---|---|---|
| Laboratory findings | ||||
| White blood cell count, × 109/L | 5.6 (4.4–7.3) | 5.5 (4.2–7.3) | 5.7 (4.5–7.3) | 0.091 |
| Neutrophil count, × 109/L | 3.6 (2.5–5.3) | 3.7 (2.5–5.6) | 3.6 (2.6–5.3) | 0.910 |
| Lymphocyte count, × 109/L | 1.1 (0.8–1.6) | 1.0 (0.7–1.4) | 1.3 (0.9–1.7) | <0.001 |
| Hemoglobin, g/L | 125.0 (114.0–135.0) | 125.0 (114.0–133.0) | 125.0 (115.0–135.0) | 0.531 |
| Anemia | 381 (35.4) | 132 (36.8) | 249 (34.7) | 0.499 |
| Platelet count, × 109/L | 214 (168.0–273.0) | 207 (158.0–270.5) | 219.0 (174.0–277.0) | 0.006 |
| Albumin, g/L | 38.0 (34.4–41.1) | 36.8 (33.7–40.0) | 38.5 (34.7–41.4) | <0.001 |
| ALT, U/L | 25.0 (17.0–42.0) | 26.0 (17.0–41.0) | 24.0 (16.0–42.0) | 0.607 |
| AST, U/L | 25.0 (19.0–38.0) | 27.0 (20.0–40.0) | 24.0 (18.0–38.0) | 0.008 |
| Urea, mmol/L | 4.7 (3.7–6.2) | 4.8 (3.7–6.5) | 4.7 (3.7–6.1) | 0.332 |
| Creatinine, μmol/L | 59.0 (49.0–71.0) | 59.0 (49.0–73.0) | 59.0 (50.0–70.0) | 0.639 |
| LDH, U/L | 237.0 (188.0–325.0) | 258.0 (200.0–355.0) | 227.0 (181.0–309.0) | <0.001 |
| PT, s | 11.9 (11.2–12.6) | 12.0 (11.3–12.7) | 11.8 (11.2–12.5) | 0.008 |
| APTT, s | 27.5 (25.6–29.9) | 27.8 (25.7–30.8) | 27.3 (29.4–25.5) | 0.009 |
| CRP, mg/L | 16.8 (3.0–60.5) | 30.8 (9.4–68.9) | 9.4 (2.4–54.1) | <0.001 |
| D-dimer, μg/mL | 0.7 (0.4–1.9) | 0.9 (0.4–2.5) | 0.6 (0.3–1.6) | <0.001 |
| Procalcitonin, ng/mL | 0.05 (0.03–0.10) | 0.06 (0.04–0.14) | 0.05 (0.03–0.09) | <0.001 |
| Glu, mmol/L | 5.5 (4.8–6.9) | 5.6 (4.9–7.1) | 5.3 (4.8–6.7) | 0.007 |
| Na, mmol/L | 141.0 (139.0–145.0) | 141.0 (138.0–144.0) | 142.0 (139.0–145.0) | 0.009 |
| K, mmol/L | 4.0 (3.7–4.3) | 4.0 (3.6–4.4) | 4.0 (3.7–4.3) | 0.376 |
| Ca, mmol/L | 2.1 (2.0–2.2) | 2.1 (2.0–2.2) | 2.2 (2.1–2.3) | <0.001 |
| Radiologic findings | ||||
| Bilateral | 843 (78.3) | 301 (83.8) | 542 (75.5) | 0.002 |
| Ground-glass opacity | 656 (60.9) | 225 (62.7) | 431 (60.0) | 0.401 |
| Patchy shadows | 612 (56.8) | 165 (46.0) | 447 (62.3) | <0.001 |
| Diffuse interstitial infiltrations | 14 (1.3) | 8 (2.2) | 6 (0.8) | 0.083 |
Data are median (IQR) or n (%). p-values were calculated using Mann-Whitney U-test, χ2-test, or Fisher's exact-test, as appropriate. GI, gastrointestinal; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactic dehydrogenase; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein.