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Genotype distribution of pups from intercrosses of Lman1+/− and Mcfd2+/− mice
| Genotype | P, χ2 | ||
|---|---|---|---|
| Lman1−/− | Lman1+/− or Lman1+/+ | ||
| Observed | 48 | 217 | <.01 |
| Expected | 66 | 199 | |
| Mcfd2−/− | Mcfd2+/− or Mcfd2+/+ | ||
| Observed | 61 | 204 | >.45 |
| Expected | 66 | 199 | |
Intercrosses between mice doubly heterozygous for Lman1-– and Mcfd2– were performed to generate double-null Lman1−/− mice, Mcfd2−/− mice, and littermate controls; 265 mice of the 9 possible expected genotypes were generated (Table 3).
