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. 2020 Nov 24;4(22):5863–5867. doi: 10.1182/bloodadvances.2020002537

Table 2.

Mechanisms responsible for the inadequate immune response in lymphoma

Mechanisms
• Loss of MHC expression on malignant B cells
• Increased expression of immunosuppressive ligands on lymphoma cells
• Suppressive immune cell populations in the TME
• Secreted cytokines that promote immune exhaustion or suppression