Table 4.
Multivariable logistic model assessment of clinical features and exposure to treatment as risk factors for hospitalization for CAP in patients with ITP
| Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Severe bleeding | 3.683 (2.749-4.935) | <.001 | 2.495 (1.726-3.608) | <.001 |
| Ever smoking | 2.211 (1.589-3.077) | <.001 | 2.182 (1.411-3.374) | <.001 |
| Exposure to corticosteroids | 2.723 (2.037-3.639) | <.001 | 3.080 (2.058-4.608) | <.001 |
| Exposure to danazol | 2.986 (1.724-5.173) | <.001 | 1.603 (0.732-3.508) | .238 |
| Exposure to intravenous immunoglobulin | 2.167 (1.449-3.240) | <.001 | 1.193 (0.659-2.158) | .560 |
| Exposure to immunosuppressive agents | 2.993 (1.959-4.573) | <.001 | 1.910 (1.043-3.498) | .036 |
| Exposure to rituximab | 3.367 (1.550-7.313) | .002 | 2.421 (0.705-8.308) | .160 |
The model was adjusted by the identified risk factors in the univariable logistic regression model (male sex, age 60 years or older, CCI score of 3 or more, initial platelet count of <20 × 109/L, and initial ALC of <1 × 109/L, all at ITP diagnosis).