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. 2020 Nov 20;4(22):5762–5771. doi: 10.1182/bloodadvances.2020002814

Table 2.

Multivariable analysis for EFS and OS in the training cohort

Covariate HR 95% CI P
EFS
 sIPI .001
  Low 1
  Low-intermediate 2.52 1.26-5.04
  High-intermediate or high 3.62 1.79-7.32
 Pretransplant DS <.001
  1-3 1
  4 3.01 1.71-5.31
  5 13.46 5.99-30.22
 B symptoms .021
  Absence 1
  Presence 1.97 1.11-3.52
 Bulky disease .730
  No 1
  Yes 0.90 0.50-1.64
 Response to previous therapy .570
  ≥1 y 1
  <1 y or refractory disease 1.18 0.66-2.10
OS
 sIPI <.001
  Low 1
  Low-intermediate 2.34 0.99-5.53
  High-intermediate or high 5.22 2.28-11.96
 Pretransplant DS <.001
  1-3 1
  4 3.35 1.76-6.38
  5 9.63 3.78-24.52
 B symptoms .019
  Absence 1
  Presence 2.12 1.13-3.97
 Bulky disease .700
  No 1
  Yes 0.88 0.46-1.68
 Response to previous therapy .640
  ≥1 y 1
  <1 y or refractory disease 1.16 0.62-2.19