TABLE 1.

Cardiac morphometry and haemodynamics at the end of study

Parameters	Young	Young/ADSC	Old	Old/ADSC	Old (BP)/ADSC
No. of rats	11	12	11	10	10
Mortality, n (%)	5 (31%)	4 (25%)	3 (21%)	3 (23%)	4 (29%)
Bodyweight, g	288 ± 12	295 ± 18	604 ± 24*, †	582 ± 18*, †	597 ± 23*, †
HR, bpm	405 ± 14	402 ± 12	387 ± 12	392 ± 14	405 ± 18
LVESP, mm Hg	95 ± 5	97 ± 5	94 ± 6	96 ± 7	96 ± 5
LVEDP, mm Hg	18 ± 5	15 ± 3	19 ± 3	18 ± 5	16 ± 4
LVW/BW, mg/g	2.64 ± 0.29	2.78 ± 0.24	2.78 ± 0.22	2.62 ± 0.19	2.79 ± 0.26
RVW/BW, mg/g	0.94 ± 0.26	0.61 ± 0.24*	1.25 ± 0.19*, †	0.89 ± 0.18 † , ‡	0.70 ± 0.22*, §
LungW/BW, mg/g	7.54 ± 0.54	5.17 ± 0.49*	8.73 ± 0.38*, †	5.82 ± 0.40 † , ‡	4.92 ± 0.44*, §
+dp/dt, mm Hg/s	2341 ± 234	3183 ± 255*	2012 ± 251*, †	2873 ± 254 † , ‡	3282 ± 265*, §
−dp/dt, mm Hg/s	2115 ± 258	2872 ± 262*	1663 ± 223*, †	2408 ± 283 † , ‡	2748 ± 238*, §
Infarct size, %	40 ± 2	41 ± 3	38 ± 3	40 ± 3	41 ± 2

Values are mean ± SD.

Abbreviations: BP, n‐butylidenephthalide; BW, bodyweight; HR, heart rate; LungW, lung weight; LVEDP, left ventricular end‐diastolic pressure; LVESP, left ventricular end‐systolic pressure; LVW, left ventricular weight; RVW, right ventricular weight.

^* P < .05, compared with young.

^† P < .05, compared with the infarcted group treated with young/ADSC.

^‡ P < .05 compared with old.

^§ P < .05 compared with old/ADSC.