Figure 3.

Effects of streptozotocin and empagliflozin on cardiac function in mice. Panels A, Ejection Fraction (EF) and B, Fractional Shortening (FS) measured by echocardiography in the different treatment groups such as control (vehicle), streptozotocin‐treated mice and streptozotocin + empagliflozin‐treated mice. Panels C, Representative M‐mode and B‐mode images recorded by echocardiography in the different treatment groups. Data are expressed as means ± standard deviations (n = 5 mice per treatment group). **P < .01 vs vehicle‐treated mice; ^°° P < .01 vs without empagliflozin. E, empagliflozin; STZ, streptozotocin