Figure 1.

SP promotes secretion of angiogenic factors in late passage MSCs in vitro. MSCs at passages 8 were inoculated in 24‐well plates at a concentration of 2 × 10⁴ cells/well. SP (1, 10, 100 and 1000 nM) was added to p8 MSCs and 24 h later, conditioned medium was collected. The amounts of SDF‐1α (A), VEGF (B) and PDGF‐BB (C) in the MSC‐conditioned medium were measured using ELISA. Values of P < .05 were considered statistically significant (*P < .05, **P < .01, ***P < .001). The data are represented as mean ± SD of three independent experiments