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. 2020 Nov 25;371:m4104. doi: 10.1136/bmj.m4104

Table 3.

Results of analyses examining associations between anaesthetic technique and secondary outcomes among the 20 988 study patients who underwent lower limb revascularisation surgery

Secondary outcomes Unadjusted odds ratio (95% CI) P value Adjusted odds ratio (95% CI) P value
In-hospital cardiac, pulmonary, or renal complications* 0.74 (0.66 to 0.83) <0.001 0.73 (0.63 to 0.85) <0.001
Major adverse cardiac event† 0.80 (0.69 to 0.92) <0.001 0.72 (0.60 to 0.87) <0.001
Heart failure 0.90 (0.71 to 1.13) 0.39
Pneumonia 0.74 (0.57 to 0.96) 0.02 0.81 (0.60 to 1.11) 0.19
Venous thromboembolism 0.42 (0.24 to 0.73) 0.001
Deep vein thrombosis 0.52 (0.29 to 0.95) 0.04
Pulmonary embolism 0.17 (0.04 to 0.70) 0.004
Acute kidney injury 0.48 (0.34 to 0.67) <0.001
Cerebrovascular event§ 0.38 (0.16 to 0.90) 0.03
Hospital readmissions 1.00 (0.91 to 1.10) 0.98 0.59 (0.32 to 1.10) 0.11
Length of hospital stay (days) Absolute difference −0.2 (−0.1 to −0.2) <0.001 Absolute difference −0.5 (−0.3 to −0.6) <0.001
*

It was decided a priori to analyse the adjusted odds of in-hospital cardiopulmonary and renal complications as a composite outcome to improve power.

Includes acute coronary syndrome, heart failure, ventricular arrhythmia, or cardiac arrest.

Number of events was too low to allow for fully adjusted regression modelling.

§

Post hoc analysis; includes transient ischaemic attack and ischaemic or haemorrhagic stroke.