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Serum total C5 concentrations over time [mean (95% CI)]. (A) Study 301. (B) Study 302. Lower limit of quantitation was 2·50 µg/ml. Baseline was defined as the last non‐missing assessment value prior to the first dose of study drug. Two patients treated with eculizumab in Study 301 had missing baseline values and were omitted from this analysis. BL, baseline; C5, complement component 5; CI, confidence interval. [Colour figure can be viewed at wileyonlinelibrary.com]
