Table 1.
Baseline characteristics by high‐sensitivity C‐reactive protein subgroup
| Baseline characteristic | Total | hsCRP <1.0 mg/L n = 53 | hsCRP 1.0–3.0 mg/L n = 92 | hsCRP >3.0 mg/L n = 183 | P‐valuea |
|---|---|---|---|---|---|
| N = 328 | (16.2%) | (28.0%) | (55.8%) | ||
| Age, years, median (IQR) | 68.0 (58.0–76.0) | 69.0 (60.0–78.0) | 70.0 (60.8–79.2) | 66.0 (57.0–74.5) | 0.035 |
| BMI, kg/m2, median (IQR) | 27.6 (24.0–31.4) | 26.5 (23.7–29.6) | 27.1 (24.0–30.9) | 28.2 (24.5–31.9) | 0.041 |
| Female sex, n | 69 (21.0%) | 15 (28.3%) | 21 (22.8%) | 33 (18.0%) | 0.231 |
| Non‐White race, n | 78 (23.8%) | 15 (28.3%) | 21 (22.8%) | 42 (23.0%) | 0.716 |
| NYHA class III/IV, n | 139 (42.4%) | 16 (30.2%) | 40 (43.5%) | 83 (45.4%) | 0.140 |
| Atrial fibrillation, n | 157 (47.9%) | 29 (54.7%) | 46 (50.0%) | 82 (44.8%) | 0.402 |
| Arterial hypertension, n | 254 (77.4%) | 44 (83.0%) | 65 (70.7%) | 145 (79.2%) | 0.163 |
| Coronary artery disease, n | 167 (50.9%) | 25 (47.2%) | 48 (52.2%) | 94 (51.4%) | 0.844 |
| Chronic kidney disease, n | 121 (36.9%) | 20 (37.7%) | 25 (27.2%) | 76 (41.5%) | 0.063 |
| Diabetes mellitus, n | 155 (47.3%) | 21 (39.6%) | 43 (46.7%) | 91 (49.7%) | 0.421 |
| DBP, mmHg, median (IQR) | 75.2 (69.6–81.7) | 75.3 (69.0–79.7) | 75.3 (68.3–82.0) | 75.0 (70.0–83.0) | 0.814 |
| SBP, mmHg, median (IQR) | 121.7 (115.6–134.4) | 120.0 (114.7–128.7) | 125.3 (117.0–135.5) | 121.0 (115.0–136.5) | 0.104 |
| Heart rate, b.p.m., median (IQR) | 70.5 (62.0–81.0) | 69.3 (61.0–78.7) | 71.0 (60.7–81.5) | 70.7 (63.1–81.2) | 0.655 |
| LVEF, %, median (IQR) | 29.2 (23.3–36.0) | 29.8 (24.5–33.9) | 31.2 (24.9–36.8) | 28.5 (23.0–37.1) | 0.350 |
| Serum sodium, mmol/L, median (IQR) | 139.0 (137.0–141.0) | 139.0 (137.0–141.0) | 139.5 (137.0–141.0) | 139.0 (136.0–140.0) | 0.194 |
| Serum creatinine, mg/dL, median (IQR) | 1.2 (1.0–1.4) | 1.1 (1.0–1.3) | 1.2 (1.0–1.4) | 1.2 (1.0–1.5) | 0.397 |
| eGFR, mL/min/1.73 m2, median (IQR) | 56.3 (44.4–72.6) | 55.3 (47.9–64.6) | 56.3 (41.3–75.0) | 56.3 (44.5–73.8) | 0.689 |
BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; hsCRP, high‐sensitivity C‐reactive protein; IQR, interquartile range; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; SBP, systolic blood pressure.
a
P‐values are based on Fisher's exact tests for sex, race, NYHA class, atrial fibrillation, arterial hypertension, coronary artery disease, chronic kidney disease and diabetes mellitus, and on Kruskal–Wallis tests for other baseline characteristics.