TABLE 3.
Parameters and generalization to nine classes
| Pre | Post |
|
τdecay | USE | D | F | NRRP | |
|---|---|---|---|---|---|---|---|---|
| PC to PC (E2) | ||||||||
| PC | PC | 0.6 ± 0.1 | 3 ± 0.2 | 0.5 ± 0.02a | 671 ± 17a | 17 ± 5a | 2 | |
| PC to SOM+ (E1) | ||||||||
| PC | OLM | 0.8 ± 0.05 | 1.7 ± 0.14 a | 0.09 ± 0.12 a | 138 ± 211 a | 670 ± 830 a | 1 | |
| PC | SOM+ | 0.8 ± 0.05 | 1.7 ± 0.14 a | 0.09 ± 0.12 a | 138 ± 211 a | 670 ± 830 a | 1 | |
| PC to SOM− (E2) | ||||||||
| PC | PVBC | 2 ± 0.05 | 4.12 ± 0.5 | 0.23 ± 0.09 | 410 ± 190 | 10 ± 11 | 1 | |
| PC | CCKBC | 3.5 ± 0.4 | 4.12 ± 0.5 | 0.23 ± 0.09 | 410 ± 190 | 10 ± 11 | 1 | |
| PC | BS | 1.65 ± 0.1 | 4.12 ± 0.5 | 0.23 ± 0.09 | 410 ± 190 | 10 ± 11 | 1 | |
| PC | Ivy | 2.3 ± 0.4 | 4.12 ± 0.5 | 0.5 ± 0.022 | 671 ± 17a | 17 ± 5a | 1 | |
| PC | SOM− | 2.35 ± 0.7 | 4.12 ± 0.5 | 0.23 ± 0.09 | 410 ± 190 | 10 ± 11 | 1 | |
| PV+ to PC (I2) | ||||||||
| PVBC | PC | 2.15 ± 0.2 | 5.94 ± 0.5 | 0.16 ± 0.02 | 965 ± 185 | 8.6 ± 4.3 | 6 | |
| AA | PC | 2.4 ± 0.1 | 11.2 ± 0.9 | 0.1 ± 0.01 | 1,278 ± 760 | 10 ± 6.7 | 1 | |
| BS | PC | 1.6 ± 0.1 | 16.1 ± 1.1 | 0.13 ± 0.03 | 1,122 ± 156 | 9.3 ± 0.7 | 1 | |
| PV+ | PC | 2 ± 0.35 | 11.1 ± 4.1 | 0.13 ± 0.03 | 1,122 ± 156 | 9.3 ± 0.7 | 1 | |
| CCK+ to PC (I3) | ||||||||
| CCKBC | PC | 1.8 ± 0.3 | 9.35 ± 1 | 0.16 ± 0.04 | 153 ± 120 | 12 ± 3.5 | 1 | |
| SCA | PC | 2.15 ± 0.3 | 8.3 ± 0.44 | 0.15 ± 0.03 | 185 ± 32 | 14 ± 5.8 | 1 | |
| CCK+ | PC | 2 ± 0.15 | 8.8 ± 0.25 | 0.16 ± 0.01 | 168 ± 15 | 13 ± 0.5 | 1 | |
| SOM+ to PC (I2) | ||||||||
| Tri | PC | 1.4 ± 0.3 | 7.75 ± 0.9 | 0.3 ± 0.08 a | 1,250 ± 520 a | 2 ± 4 a | 1 | |
| SOM+ | PC | 1.4 ± 0.3 | 8.3 ± 2.2 a | 0.3 ± 0.08 a | 1,250 ± 520 a | 2 ± 4 a | 1 | |
| NOS+ to PC (I3) | ||||||||
| Ivy | PC | 0.48 ± 0.05 | 16± 2.5 | 0.32 ± 0.14a | 144 ± 80a | 62 ± 31a | 1 | |
| CCK− to CCK− (I2) | ||||||||
| PVBC | PVBC | 4.5 ± 0.3 | 2.67 ± 0.13 | 0.26 ± 0.05 | 930 ± 360 | 1.6 ± 0.6 | 6 | |
| PVBC | AA | 4.5 ± 0.3 | 2.67 ± 0.13 | 0.24 ± 0.15 | 1,730 ± 530 | 3.5 ± 1.5 | 1 | |
| CCK− | CCK− | 4.5 ± 0.3 | 2.67 ± 0.13 | 0.26 ± 0.05 | 930 ± 360 | 1.6 ± 0.6 | 1 | |
| CCK+ to CCK+ (I1) | ||||||||
| CCKBC | CCKBC | 4.5 ± 0.3 | 4.5 ± 0.55 | 0.11 ± 0.03 | 115 ± 110 | 1,542 ± 700 | 1 | |
| CCK+ | CCK+ | 4.5 ± 0.3 | 4.5 ± 0.55 | 0.11 ± 0.03 | 115 ± 110 | 1,542 ± 700 | 1 | |
Note: Synapse parameters either taken from the literature (τdecay (ms)), fitted directly to data (USE, D (ms), F (ms)), calibrated in silico ( (nS), NRRP) or taken from the somatosensory cortex ((Markram et al., 2015) marked with superscript “a”). Values in the τdecay column which neither appear in Supplementary Table S1 (summarizing rat PSCs) nor are taken from the somatosensory cortex, are from mouse recordings (Daw et al., 2009; Lee et al., 2014). Average class parameters are marked in bold and are used predictively for the remaining pathways belonging to the same class. For cells belonging into the same class, see Table 2, Assumption 9. M‐type abbreviations are as in Figure 3c. [Correction added on 12 October 2020, after first online publication: Values in the above table were updated.]