Table 3.
Associations between change in QCT‐measured outcomes and change in clinical response variables
| Lobar RV change | Lobar TLC change | ||||||
|---|---|---|---|---|---|---|---|
| Parameter | Treated lobes | Untreated lobes | Total lung | Treated lobes | Untreated lobes | Total lung | |
| Change in RV (n = 78) | 0.380 (0.001) | −0.168 (0.142) | 0.165 (0.148) | 0.322 (0.004) | −0.250 (0.027) | 0.049 (0.670) | |
| Change in FEV1 (n = 78) | −0.706 (<0.001) | 0.088 (0.442) | −0.446 (<0.001) | −0.454 (<0.001) | 0.481 (<0.001) | −0.042 (0.712) | |
| Change in SGRQ (n = 78) | 0.167 (0.144) | −0.256 (0.023) | −0.041 (0.724) | 0.169 (0.140) | −0.426 (<0.001) | −0.231 (0.042) | |
| Change in 6MWD (n = 77) | −0.232 (0.042) | 0.005 (0.966) | −0.162 (0.160) | −0.111 (0.338) | 0.168 (0.145) | 0.055 (0.636) | |
| Change in lobar TLC (n = 77) | Treated lobes | 0.647 (<0.001) | −0.336 (0.003) | 0.242 (0.033) | |||
| Untreated lobes | −0.212 (0.062) | 0.364 (0.001) | 0.142 (0.216) | ||||
| All lobes | 0.327 (0.004) | −0.012 (0.915) | 0.260 (0.022) | ||||
Data are presented as Pearson correlation coefficient (P‐value). Significant P‐values are depicted in bold.
6MWD, 6‐min walk distance; FEV1, forced expiratory volume in 1 s; QCT, quantitative computed tomography; RV, residual volume; SGRQ, St George's Respiratory Questionnaire; TLC, total lung capacity.