Figure 5.

Isotransplants in vivo of embryo‐derived teratomas grown previously for 14 days in vitro. (A) Growth in vivo under the kidney capsule. Note that only controls were growing in transplants and were recovered for weighing and assessment of differentiation, while VPA‐treated teratomas did not develop at all. m(g) = mass in grams (n = 9 control embryo‐derived teratomas, n = 9 VPA‐treated embryo‐derived teratomas). Mean ± SEM. (B) Trilaminar differentiation of controls in vivo, the stratified squamous epithelium (E), the hair follicle (F), vegetative ganglion (G), muscle (M) pseudostratified columnar epithelium (arrows); scale bar = 50 μm, hematoxylin–eosin stain.