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. Author manuscript; available in PMC: 2021 Feb 12.
Published in final edited form as: J Neural Eng. 2020 Feb 12;17(1):016057. doi: 10.1088/1741-2552/ab4a22

Figure 2. Effect of MAM Concentration on Hydrogel Alignment and Mechanical Properties.

Figure 2.

A) Magnetically templated GMHA-Col hydrogels with varying MAM concentrations from 2 to 5 mg/mL. Light micrographs of longitudinal sections of freshly crosslinked aligned hydrogels, containing dark, opaque MAMs. Scale bars = 500 μm, arrow indicates the direction of magnetic alignment. B) Ratio to mean orthogonal angle derived from FFT analysis. Increasing ratio to mean orthogonal angle indicates increased morphological alignment, with 5 mg/mL MAM concentrations resulting in the highest alignment. C) Indentation compressive mechanical properties of freshly crosslinked hydrogels at varying MAM concentrations. Decreased mechanical properties noted at progressively higher MAM concentrations. For all graphs: * indicates statistically significant differences from all other groups and numbers 2-5 indicate statistically significant differences to 2-5 mg/mL MAM groups respectively. Error bars represent standard deviation.