TABLE 1.
Propensity score matched * | |||||
---|---|---|---|---|---|
Without statin exposure | With statin exposure | ||||
n | % | n | % | P‐Value | |
Number of patients | 144,301 | 144,214 | |||
Age | |||||
45 to 49 | 11,764 | 8.15% | 6157 | 4.27% | 0.99 |
50 to 54 | 10,991 | 7.62% | 7523 | 5.22% | |
55 to 59 | 11,293 | 7.83% | 9844 | 6.83% | |
60 to 64 | 9175 | 6.36% | 10,623 | 7.37% | |
65 to 69 | 35,097 | 24.32% | 37,460 | 25.98% | |
70 to 74 | 27,748 | 19.23% | 33,170 | 23.00% | |
75 to 79 | 18,073 | 12.52% | 21,233 | 14.72% | |
80 to 84 | 11,300 | 7.83% | 11,169 | 7.74% | |
85 to 89 | 2343 | 1.62% | 2717 | 1.88% | |
90 and over | 6517 | 4.52% | 4318 | 2.99% | |
Sex | |||||
Female | 82,584 | 57.23% | 75,773 | 52.54% | 0.99 |
Male | 61,717 | 42.77% | 68,441 | 47.46% | |
Ethnicity | |||||
White | 105,254 | 72.94% | 115,135 | 79.84% | 0.99 |
Black | 3269 | 2.27% | 5561 | 3.86% | |
Asian | 258 | 0.18% | 494 | 0.34% | |
Hispanic | 774 | 0.54% | 1593 | 1.10% | |
Other | 887 | 0.61% | 1316 | 0.91% | |
Unknown | 33,859 | 23.46% | 20,115 | 13.95% | |
Region | |||||
Midwest | 33,456 | 23.18% | 28,916 | 20.05% | 0.99 |
Northeast | 3053 | 2.12% | 2663 | 1.85% | |
South | 91,930 | 63.71% | 98,772 | 68.49% | |
West | 15,862 | 10.99% | 13,863 | 9.61% | |
Comorbidities | |||||
T2DM | 3817 | 2.65% | 9536 | 6.61% | 0.003 |
HTN | 12,102 | 8.39% | 13,550 | 9.40% | |
CVD | 2469 | 1.71% | 8901 | 6.17% | |
STROKE | 2361 | 1.64% | 7274 | 5.04% | |
CKD | 3500 | 2.43% | 9256 | 6.42% | |
COPD | 2192 | 1.52% | 4741 | 3.29% | |
CCI | |||||
0–4 | 117,275 | 81.27% | 138,329 | 95.92% | 0.99 |
5–10 | 24,743 | 17.15% | 5500 | 3.81% | |
11+ | 2283 | 1.58% | 385 | 0.27% |
Abbreviations: CCI, Charlson Comorbidity Index.; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; HTN, hypertension; T2DM, type‐2 diabetes mellitus.
Adjusted for age, sex, region, comorbidities and CCI.