Table 1.

Differences in PHX and DILI models relevant to liver regeneration

Parameter	Partial Hepatectomy	DILI
Point of initiation	Well defined, within minutes after surgery	Not well defined, depends on cellular damage
Role of Inflammation	Minor inflammatory response	Significant inflammatory response
Cell cycle progression	Synchronized	Unsynchronized (depends on extent of cell death)
Cell proliferation	All hepatocytes in the remnant liver divide	Hepatocytes surrounding the necrotic zone divide