Table 1.

Comparison of clinicopathological characteristics of patients treated during COVID-19 pandemic caused hospital lock down and outside of the pandemic in the West of Scotland.¹ Data was not available for 12 patients in the COVID database and 717 patients had either cT0, or primary tumour was not assessed in the MCN database.² Data was not available for 11 patients in the COVID database and 26 patients lymph nodes were not assessed or recorded in the MCN database.³ Final pathology is awaiting in 7 patients in the COVID database and primary tumour subtype was not assessable or recorded in 19 patients in the MCN database.⁴ Grade not assessable or not applicable in 218 patients in the MCN database. Grade, ER status and HER-2 status were determined in invasive cancer only.

		COVID-19 database		MCN database		P value
Clinicopathological characteristics		No. of patients (%)		No. of patients (%)
Presentation	symptomatic	116	64.8%	749	52.9%	<0.001 CS
	screener	57	31.8%	469	33.1%
	other	6	3.3%	197	13.9%
cT1	cTis	7	4.2%	132	6.3%	<0.001 CS
	cT1	57	34.1%	685	32.7%
	cT2	75	44.9%	1121	53.6%
	cT3-4	28	16.8%	154	7.4%
cN2	cN0	127	75.1%	1125	80.9%	0.099 (NS)
	cN1-3	41	24.9%	265	19.1%
Tumour subtype3	DCIS/LCIS	8	4.7%	116	8.3%	0.057 MW
	Ductal	126	73.7%	988	70.8%
	Lobular	22	12.7%	152	10.9%
	Mixed	3	1.7%	16	1.1%
	Mucinous	2	1.2%	22	1.5%
	Tubular	2	1.2%	15	1.1%
	Papillary	2	1.2%	5	0.3%
	Other	5	2.9%	71	5.1%
	Inflammatory	1	0.6%	11	0.8%
(y)pT	yPt0	10	5.9%	N/A	N/A	0.002 CS
	(y)pTis	11	6.5%	116	10.1%
	(y)pT1	71	42%	619	54.1%
	(y)pT2	57	33.7%	344	30.1%
	(y)pT3 – T4	20	11.8%	64	5.6%
Grade4	G1	11	6.8%	96	9.1%	0.107 (NS) CS
	G2	70	43.2%	522	49.5%
	G3	81	50%	436	41.3%
ER expression4	negative	67	41.3%	217	17%	<0.001
HER-2 expression4	positive	38	23.4%	188	14.8%	= 0.004
(y)pN4	(y)pN0	112	69.1%	711	68.2%	= 0.791 (NS)
	(y)pN1	36	22.2%	253	24.2%
	pN2	8	4.9%	53	5.1%
	pN3	6	3.7%	26	2.5%