Fig. 5.

hucMSC-Exos improved the respiratory function damaged by silica in mice (n = 4). The flexiVent FX system was used to test the lung function, and results were compared with the reference value. a Inspiratory capacity was performed by the model of Deep Inflation. b–d Respiratory resistance, elastic resistance, and static compliance were performed by the model of Snap Shot. e–g Airway resistance, tissue damping, and tissue elastance were measured by the Prime wave. h FEV model was applied to measure the FEV0.1. i–k PV loops were used to assess static compliance, total lung capacity, and form of deflating PV loop. PV loop baseline was measured by the PV loops. This was separately calculated for each group. The data are presented as means ± SD (n = 4). *P < 0.05 compared with the control group, ^#P < 0.05 compared with the silica group