Table 1. Transgenic Flp mouse lines for intersectional biology.
Transgenic lines were located using a range of search methods. Lines no longer maintained are included for completeness.
| Driver | Flp Gene | Genetics | Source | Original Citation | INTRSECT Citation |
|---|---|---|---|---|---|
| Actb | FlpE | A | Jackson: 003800 | Rodriguez et al., 2000 | |
| Atoh1 | FlpO-ER | A | joynera@mskcc.org | Wojcinski et al., 2019 | |
| Bhlhe22 | FlpO | C | saross@pitt.edu | Cai et al., 2016 | |
| Cag | FlpE | A | RBRC: 10707, 10708 | Kanki et al., 2006 | |
| Cag | FlpE-ER | A | No longer maintained | Hunter et al., 2005 | |
| CamK2a | FlpE | Taconic - Not available | |||
| Cdx2 | FlpO | A | Jackson: 030288 | Abraira et al., 2017 | |
| Cdx2 | FlpO | A | goulding@salk.edu | Britz et al., 2015 | |
| Crh | FlpO | D | Jackson: 031559 | Unpublished | |
| DbH | FlpO | C | Jackson: 033952 | Robertson et al., 2013 | |
| DbH | FlpO | C | MMRRC: 41577 | Sun and Ray, 2016 | |
| DbH | FlpO | E | MMRRC: 41575 | Sun and Ray, 2016 | |
| Dlx5/6 | Myc-FlpE | A | Jackson: 010815 | Miyoshi et al., 2010 | Wick et al., 2019 |
| EF1A | Flp | A | RBRC: 01251, 01252 | Takeuchi et al., 2002 | |
| Fezf2 | FlpO | E | huangj@cshl.edu | Unpublished | |
| Gad2 | FlpO | D | hantmana@janelia.hhmi.org | Alhadeff et al., 2018 | |
| GFAP | FlpO | A | Jackson: 33116 | Hara and Verma, 2019 | |
| Gsh2 | FlpE | D | CARD: 2114 | Unpublished | |
| Hcrt | FlpO | E | yamank@riem.nagoya-u.ac.jp | Chowdhury et al., 2019 | |
| Hoxb8 | FlpO | A | EMMA: 11094 | Zhang et al., 2018 | |
| Htr3a | FlpO | D | Jackson: 030755 | Schuman et al., 2019 | |
| Lbx1 | FlpO | C | goulding@salk.edu | Bourane et al., 2015 | |
| mGluR6 | FlpO | A | RBRC: 09715 | Unpublished | |
| MMTV | FlpO | A | gerhard.christofori@unibas.ch | Lüönd et al., 2019 | |
| Mrgprb4 | EGFP-2aFlpO | F | Jackson: 021078 | Vrontou et al., 2013 | |
| Nestin | FlpO-ER | A | joynera@mskcc.org | Lao et al., 2012 | |
| Nkx2.1 | FlpO | D | Jackson: 28577 | He et al., 2016 | |
| Nphs1 | FlpO | A | minerj@wustl.edu | Goldberg et al., 2010 | |
| Npy | FlpO | D | Jackson: 030211 | Daigle et al., 2018 | |
| Pdx1 | FlpO | A | dieter.saur@tum.de | Schönhuber et al., 2014 | |
| Pdx1 | FlpO | C | ostrowsk@musc.edu | Wu et al., 2017 | |
| Pet1 | FlpE | A | dymecki@genetics.med.harvard.edu | Jensen et al., 2008 | |
| Pgk1 | FlpO | A | Jackson: 011065 | Wu et al., 2009 | |
| Phox2b | FlpO | B | Jackson: 022407 | Hirsch et al., 2013 | |
| Prkcd | FlpO | E | bli@cshl.edu | Unpublished | |
| PlexinD1 | FlpO | E | huangj@cshl.edu | Unpublished | |
| Plxnd1 | dgFlpO | D | tanyad@alleninstitute.org | Daigle et al., 2018 | |
| Pomc | FlpE | A | No longer maintained | Vooijs et al., 1998 | |
| Pvalb | FlpE | E | Jackson: 021191 | Madisen et al., 2015 | |
| Pvalb | FlpO | E | Jackson: 022730 | Madisen et al., 2015 | Hafner et al., 2019 |
| Pvalb* | FlpO | E | joshua.berke@ucsf.edu | Unpublished | |
| Rasgrf2 | dgFlpO | E | Jackson: 029589 | Daigle et al., 2018 | |
| Rorb | FlpO | D | Jackson: 029590 | Daigle et al., 2018 | |
| Rorb | FlpO | E | tanyad@alleninstitute.org | Daigle et al., 2018 | |
| Slc17a6 | FlpO | D | Jackson: 030212 | Daigle et al., 2018 | |
| Slc32a1 | FlpO | D | Jackson: 031331 | Daigle et al., 2018 | |
| Slc32a1 | FlpO | E | Jackson: 029591 | Daigle et al., 2018 | Lazaridis et al., 2019 |
| Slc6a3 | FlpO | D | Jackson: 033673 | Unpublished | |
| Slc6a4 | FlpO | D | Jackson: 033674 | Unpublished | |
| SST | FlpO | D | Jackson: 028579 | He et al., 2016 | Clemente et al., 2017 Cummings et al., 2020 Fadok et al., 2017 Fenno et al., 2014 Yu et al., 2017 |
| Tbr2 | FlpO-ER | E | huangj@cshl.edu | Unpublished | |
| Tbx21 | FlpE-ER | D | Graham.lord@manchester.ac.uk | Gökmen et al., 2013 | |
| TH | FlpO | E | MMRRC: 50618 | Poulin et al., 2018 | Chuhma et al., 2018 Poulin et al., 2018 Mingote et al., 2019 |
| TH | FlpO | A | RBRC: 5168–5171 | Imayoshi et al., 2012 | |
| Trf | FlpE | Taconic - Not available | |||
| Tshz1 | FlpO | E | bli@cshl.edu | Unpublished | |
| VGlut2 | FlpO | D | hantmana@janelia.hhmi.org | Alhadeff et al., 2018 | |
| VIP | FlpO | D | Jackson: 028578 | He et al., 2016 | |
| Wnt1 | Flp(F70L) | A | No longer maintained | Dymecki et al., 1998 | |
| Wnt1 | FlpE-ER | A | No longer maintained | Hunter et al., 2005 | |
| Wnt1 | FlpE | A | dymecki@genetics.med.harvard.edu | Awatramani et al., 2003 |
Any reference to contact individuals was approved. Online version with functionality to add lines is maintained at www.optogenetics.org/flp_lines.html.
*
transgenic rat line. A: Random Integration; B: BAC transgenic; C: START knock-in; D: IRES knock-in; E: 2a knock-in; F: 2a knock-in/driver knock-out. Jackson: Jackson Laboratory, http://www.jax.org; RBRC: Riken BioResource Research Center, https://mus.brc.riken.jp/en/; MMRRC: Mutant Mouse Resource & Research Centers, https://www.mmrrc.org; CARD: Center for Animal Resources and Development, http://cardb.cc.kumamoto-u.ac.jp/transgenic/index.jsp; EMMA: European Mouse Mutant Archive, https://www.infrafrontier.eu/