Table 2.

Risk of stroke, myocardial infarction, and both according to TyG index quartile

TyG index	Events (n)	Duration (person-years)	Incidence rate (per 1000 person-years)	Model 1, hazard ratio (95% CI)	Model 2, hazard ratio (95% CI)	Model 3, hazard ratio (95% CI)
Myocardial infarction and stroke
Q1	26,773	11,447,594.33	2.33874	1 (ref.)	1 (ref.)	1(ref.)
Q2	33,335	11,430,071.25	2.91643	1.247 (1.227, 1.267)	1.18 (1.161, 1.199)	1.085 (1.068, 1.103)
Q3	39,119	11,416,557.3	3.42651	1.466 (1.443, 1.489)	1.338 (1.317, 1.359)	1.157 (1.138, 1.176)
Q4	47,517	11,384,076.25	4.17399	1.786 (1.759, 1.813)	1.608 (1.584, 1.633)	1.282 (1.262, 1.304)
p for trend				< .0001	< .0001	< .0001
Myocardial infarction
Q1	11,223	11,503,460.68	0.97562	1 (ref.)	1 (ref.)	1 (ref.)
Q2	14,124	11,500,096.33	1.22816	1.257 (1.226, 1.289)	1.204 (1.174, 1.234)	1.092 (1.065, 1.12)
Q3	16,618	11,499,511.73	1.4451	1.48 (1.444, 1.516)	1.379 (1.346, 1.412)	1.165 (1.137, 1.194)
Q4	20,612	11,483,933.86	1.79486	1.837 (1.795, 1.88)	1.697 (1.658, 1.737)	1.312 (1.28, 1.345)
p for trend				< .0001	< .0001	< .0001
Stroke
Q1	16,378	11,483,024.16	1.42628	1 (ref.)	1 (ref.)	1 (ref.)
Q2	20,315	11,474,799.11	1.7704	1.242 (1.217, 1.268)	1.164 (1.14, 1.188)	1.080 (1.058, 1.103)
Q3	23,806	11,469,602.92	2.07557	1.457 (1.428, 1.486)	1.306 (1.28, 1.333)	1.148 (1.125, 1.172)
Q4	28,621	11,450,595.06	2.49952	1.754 (1.72, 1.788)	1.545 (1.515, 1.575)	1.260 (1.234, 1.287)
p for trend				< .0001	< .0001	< .0001

Model 1: crude

Model 2: adjusted for age and sex

Model 3: adjusted for age, sex, smoking, alcohol consumption, regular physical activity, low socioeconomic status, body mass index, hypertension, total cholesterol level, hypertension medications, warfarin, and aspirin