Fig. 6.

The improved anti-adhesion effect of HCPT-EVs was attributed to activation of the ERS pathway. a Representative WB images of GRP78, CHOP, Bax, and Bcl-2. b BCA was applied to determine the total protein concentration of EVs. Rat fibroblasts were treated with salubrinal (10 μM) for 1 h before incubation with Unprimed EVs or HCPT-EVs (100 μg/mL) in the presence of TGF-β1 (2 ng/ml) for 48 h. c Representative WB images of COL III and α-SMA. d, e Semiquantitative analysis of COL III and α-SMA. *P < 0.05, **P < 0.01, ***P < 0.001; ns, not significant