Table 1.
Effect of continentalic acid on CBC
| Parameters | WBC count (109/L) |
LYM (109/L) |
NEU (109/L) |
RBC (1012/L) |
PLT (109/L) |
|---|---|---|---|---|---|
| Vehicle control | 4.4 ± 0.17 | 3.6 ± 0.90 | 2.5 ± 0.12 | 4.62 ± 0.19 | 189 ± 10 |
| LPS treated | 8.5 ± 0.11### | 6.9 ± 0.17### | 6.5 ± 0.08 ### | 4.41 ± 0.13### | 185 ± 16### |
| LPS + Vehicle | 8.34 ± 0.20### | 7.12 ± 0.05### | 6.7 ± 0.10 ### | 4.32 ± 0.41### | 184 ± 8### |
| Dexa 10 mg/kg | 4.5 ± 0.21*** | 3.8 ± 0.11 | 2.60 ± 0.12*** | 4.49 ± 0.30 | 183 ± 10 |
| CNT 10 mg/kg | 6.5 ± 0.23 | 4.90 ± 0.09 | 5.01 ± 0.12 | 4.34 ± 0.11 | 189 ± 22 |
| CNT 50 mg/kg | 4.8 ± 0.15** | 4.30 ± 0.12 | 2.70 ± 0.15** | 4.51 ± 0.40 | 188 ± 13 |
| CNT 100 mg/kg | 4.4 ± 0.10*** | 3.70 ± 0.15 | 2.62 ± .90 *** | 4.50 ± 0.09 | 182 ± 9 |
All data were expressed as mean (n = 8) ± SD
###p < 0.001compared to control group
***p < 0.001compared to negative control group